Explain the role of major histocompatibility complex (MHC) molecules and human leukocyte antigen (HLA) genes in organ transplant and rejection

What will be an ideal response?


Compatibility between organ donor and organ recipient is determined through a process that screens the antigens most likely to cause rejection—those associated with MHC molecules, which are encoded on genes called human leukocyte antigen (HLA) genes. A donor individual who has a high percentage of HLA similarity to the recipient is said to be a match. Exact HLA matches are rare and most likely to be found within families.

Anatomy & Physiology

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Skeletal, cardiac, and smooth muscle cells are cells that move organs and body parts

Indicate whether the statement is true or false

Anatomy & Physiology

Visceral motor neuron nuclei are located in which part of the brain?

A) midbrain B) primary motor cortex C) hypothalamus D) thalamus E) cerebellum

Anatomy & Physiology

Human placental lactogen initiates labor

Indicate whether the statement is true or false

Anatomy & Physiology

When cells become active in a certain area of the body, the blood flow to the capillaries in that area must _____ to provide more ____.

A. increase, O2 B. decrease, O2 C. increase, CO2 D. decrease, sodium E. decrease, ATP

Anatomy & Physiology