Which of the following amino acids is present in Hb S and not present in normal Hb?
a. Valine
b. Glutamic acid
c. Proline
d. Histidine
ANS: A
Hb S is formed by a genetic mutation in which one amino acid (valine) replaces glutamic acid. Valine has replaced glutamic acid. Hb S is formed by a genetic mutation in the amino acid (va-line), not proline, or histidine.
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