A drug's adverse effects are based on its:

A) margin of safety
B) manufacturing process
C) date of expiration
D) frequency of use


A) margin of safety
A drug's adverse effects are based on its margin of safety, between the effective dose and the toxic dose. An overdose is usually linked to a drug with a large margin of safety, whereas adverse effects can occur from therapeutic doses when the margin of safety is small or nonexistent. Margin of safety applies to all drugs — prescription or nonprescription.

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