A client with Alzheimer disease is admitted for an overdose of donepezil (Aricept). What will the nurse most likely assess in this client?
Standard Text: Select all that apply.
1. Tachycardia
2. Vomiting
3. Muscle twitching
4. Abdominal cramping
5. Urinary retention
Correct Answer: 1,2,3,4
Rationale 1: Tachycardia is a sign of progressing cholinergic crisis.
Rationale 2: Vomiting is a sign of intense parasympathetic stimulation associated with a cholinergic crisis.
Rationale 3: Muscle twitching is a sign of intense parasympathetic stimulation associated with a cholinergic crisis.
Rationale 4: Abdominal cramping is a sign of intense parasympathetic stimulation associated with a cholinergic crisis.
Rationale 5: Urinary retention is not associated with a cholinergic crisis.
Global Rationale: Tachycardia, vomiting, muscle twitching, and abdominal cramping are signs of progressing cholinergic crisis. Urinary retention is not associated with a cholinergic crisis.
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