Progesterone maintains pregnancy but also has which of the following local effects on the body? Select all that apply
A) Decrease in absorption of sodium
B) Increase in basal body temperature
C) Increase in secretion of aldosterone by the adrenal cortex
D) Relaxation of smooth muscle
Ans: B, C, D
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Progesterone can compete with aldosterone at the level of the renal tubule, causing a decrease in sodium reabsorption, with a resultant increase in secretion of aldosterone by the adrenal cortex (as occurs in pregnancy). Although the mechanism is uncertain, progesterone increases basal body temperature and is responsible for the increase in body temperature that occurs with ovulation. Smooth muscle relaxation under the influence of progesterone plays an important role in maintaining pregnancy.
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