Which statement best describes heparin-induced thrombocytopenia (HIT)?
a. Immunoglobulin G immune–mediated adverse drug reaction that reduces circulating platelets
b. Hematologic reaction to heparin in which the bone marrow is unable to produce sufficient platelets to meet the body’s needs
c. Immunoglobulin E–mediated allergic drug reaction that reduces circulating platelets
d. Cell-mediated drug reaction in which macrophages process the heparin and platelet complexes that are then destroyed by activated cytotoxic T cells.
Ans: a. Immunoglobulin G immune–mediated adverse drug reaction that reduces circulating platelets
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