How does the proton motive force lead to production of ATP?
A) ATPase requires one proton to make one ATP.
B) Protons must be pumped against a concentration gradient from outside of the cell into the cell to rotate the F0 subunit of ATPase for the F1 subunit to make ATP.
C) Oxidative phosphorylation of ADP by ATP synthase requires protons as cofactors in the reaction.
D) Translocation of three to four protons drives the F0 component of ATPase which in turn phosphorylates one ADP into ATP.
Answer: D
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