Mike has classical hemophilia, a clotting disorder, but his case is considered "mild." Contrary to popular belief, Mike doesn't usually have problematic bleeding episodes related to cutting himself; a more severe problem for him would be brought on by a sprained ankle or by having a full body impact, like falling off a horse and landing hard on the ground, injuries considered "closed." With what
you have learned about blood coagulation, can you explain how this could be so? Assuming Mike is lacking factor VIII, which pathways does he depend on?
What will be an ideal response?
Only the intrinsic pathway requires factor VIII for activation; the extrinsic pathway and the common pathway are unaffected by the lack of factor VIII. The extrinsic pathway is activated by tissue damage, so even in a person with hemophilia, these may function at close to normal levels.
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Two areas of the vertebral column that lack intervertebral discs are the coccyx and the ________.
Fill in the blank(s) with the appropriate word(s).
________ are phagocytic cells that are permanent residents of specific tissues and organs.
Fill in the blank(s) with the appropriate word(s).
Tetanus toxin inhibits acetylcholinesterase activity. What will a person suffering from tetanus toxin poisoning look like?
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