Why is there a need to produce Okazaki fragments on the lagging strand, but not on the leading strand of DNA?

A. The two parental strands of DNA are antiparallel and DNA polymerase makes DNA in the 5? to 3? direction only.
B. It is substantially more efficient to make several shorter strands rather than one longer strand of DNA.
C. There lacks enough cellular DNA ligase for bonding Okazaki fragments together if they were produced from both parental strands.
D. By having one leading strand and one lagging strand the cell can limit the amount of DNA polymerase used for chromosomal replication.
E. It is faster to make several smaller fragments than one larger fragment.


A. The two parental strands of DNA are antiparallel and DNA polymerase makes DNA in the 5' to 3' direction only.

Biology & Microbiology

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