The nurse recognizes that which physiological change during pregnancy can alter absorption of medication?

1. Decreased levels of progesterone cause a decrease in gastric tone and intestinal motility.
2. High estrogen levels cause decreased hydrochloric acid production, which may affect the absorption of certain acid labile drugs.
3. An enlarging uterus presses against the stomach, resulting in increased gastric emptying.
4. Increased levels of progesterone increase pulmonary blood flow, resulting in higher serum levels for respiratory drugs.


Correct Answer: 4
Rationale 1: Increased levels of progesterone cause a decrease in gastric tone and intestinal motility.
Rationale 2: High estrogen levels cause increased hydrochloric acid production, which may affect the absorption of certain acid labile drugs.
Rationale 3: An enlarging uterus presses against the stomach, resulting in decreased gastric emptying.
Rationale 4: Increased levels of progesterone increase pulmonary blood flow, resulting in higher serum levels for respiratory drugs.
Global Rationale: Increased levels of progesterone increase pulmonary blood flow, resulting in higher serum levels for respiratory drugs. Increased levels of progesterone, not decreased, cause a decrease in gastric tone and intestinal motility. High estrogen levels cause increased hydrochloric acid production, which may affect the absorption of certain acid labile drugs. An enlarging uterus presses against the stomach, resulting in decreased gastric emptying.

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