Discuss possible causes of pain on injection

What will be an ideal response?


There are many possible causes of pain on injection. Needle penetrations of well-innervated anatomic structures can cause pain. Rapid deposition of solution can distend tissues, causing pain. Pain can occur due to the irritating and acidic nature of local anesthetic solutions, and can also occur if solutions are too cold or too hot compared to oral temperature.

Health Professions

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