What is the correct relationship between red cells' affinity for oxygen and red cell production?
a. When affinity is low, more oxygen is released and the body compensates by making red cells larger.
b. When affinity is low, less oxygen is released and the body compensates by increasing erythropoietin and making more red cells.
c. When affinity is high, less oxygen is released and the body compensates by increasing erythropoietin and making more red cells.
d. When affinity is high, more oxygen is released and fewer red cells are needed.
ANS: C
When hemoglobin's oxygen affinity is high, less oxygen is released to tissue. The normal physiologic response to less oxygen delivery is to increase erythropoietin and make more red cells.
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