A patient has been prescribed phenylephrine (Neo-Synephrine). Prior to administering this drug the nurse would review the patient's medication history for presence of which drugs? Note: Credit will be given only if all correct choices and no incorrect choices are selected. Standard Text: Select all that apply
1. MAO inhibitors
2. Tricyclic antidepressants
3. Iron supplements
4. Digoxin
5. Aspirin
1,2,3,4
Rationale 1: Concurrent use with MAO inhibitors may result in hypertensive crisis.
Rationale 2: Tricyclic antidepressants can potentiate the effects of phenylephrine (Neo-Synephrine).
Rationale 3: Iron supplements are incompatible with phenylephrine (Neo-Synephrine).
Rationale 4: Dysrhythmias may occur when phenylephrine (Neo-Synephrine) and digoxin are used concurrently.
Rationale 5: There is no incompatibility with aspirin.
Global Rationale: Concurrent use with MAO inhibitors may result in hypertensive crisis. Tricyclic antidepressants can potentiate the effects of phenylephrine (Neo-Synephrine). Iron supplements are incompatible with phenylephrine (Neo-Synephrine). Dysrhythmias may occur when phenylephrine (Neo-Synephrine) and digoxin are used concurrently. There is no incompatibility with aspirin.
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