Explain how X inactivation can result in female mosaicism and give examples

What will be an ideal response?


Female mammals are constructed of two different cell types. Some cells express alleles from the father's X chromosome and some cells express alleles from the mother's X chromosome. Early in embryonic development, one X chromosome in each cell will be inactivated. The inactivation will occur randomly. If a visible trait is linked to an inactivated X chromosome, any cells derived from the original inactivated cell will not display the trait. The pattern of coat color in some mice and in some cats, and the patches of affected and unaffected skin on a woman with anhidrotic ectodermal dysplasia represent groups of cells descended from a single cell in which the inactivation event occurred.

Biology & Microbiology

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Black fur in mice (B) is dominant to brown fur (b). Short tails (T) are dominant to long tails (t). What fraction of the progeny of crosses BbTt × BBtt will be expected to have black fur and long tails?

A) 1/16 B) 3/8 C) 1/2 D) 9/16

Biology & Microbiology

Magnesium chloride is a salt formed with ionic bonds between one magnesium ion and two chloride ions. Magnesium has two electrons in its outer shell and chlorine has seven electrons in its outer shell. How are the electrons transferred between these atoms?

A. Both magnesium and chlorine are reduced. B. Magnesium is oxidized and chlorine is reduced. C. Both magnesium and chlorine are oxidized. D. Chlorine is oxidized and magnesium is reduced.

Biology & Microbiology

What does the United States's population growth look like?

A. leveling off B. a rectangular column C. decreasing D. increasing E. an upside-down pyramid

Biology & Microbiology