The following DNA sequence is a small part of the coding (nontemplate) strand from the open reading frame of the B-Hemoglobin gene. Given the codon chart listed below, what would be the effect of a mutation that deletes the G at the beginning of the DNA sequence?
(A) The mutation precedes the gene, so no changes would occur.
(B) Lysine (lys) would replace glutamine (gln), but there would be no other changes.
(C) The first amino acid would be missing, but there would be no other change to the protein.
(D) The reading frame of the sequence would shift, causing a change in the amino acid sequence after that point.
Ans: (D) The reading frame of the sequence would shift, causing a change in the amino acid sequence after that point.
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