Which statement regarding the pharmacokinetics of penicillin G is correct?
1. Penicillin G is absorbed well when administered orally.
2. The absorption of intramuscular procaine and benzathine penicillin G occurs rapidly, producing high blood levels.
3. Inflammation increases the distribution of penicillin G into the joints and cerebrospinal fluid.
4. Penicillin G undergoes extensive metabolism in the liver before excretion by the kidneys.
Correct Answer: 3
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