Describe the molecular events of the heat shock response involving Hsp70
What will be an ideal response?
Answer: When temperatures are elevated, usually by just a few degrees, the complex of heat shock protein 70 (Hsp70) and heat shock factor (HSF) monomers in the cytoplasm dissociate and Hsp70 binds to denatured proteins to act as chaperones. The HSF monomers assemble into trimers, migrate into the nucleus, and bind to the promoters of genes with heat shock elements. Transcription of Hsp70 increases, ultimately resulting in the formation of more Hsp70/HSF complexes and cessation of the transcriptional cascade.
You might also like to view...
Increases in NFP result in increases in GFR
Indicate whether this statement is true or false.
During asthma, the airway narrows due to smooth muscle constriction. How can the body respond to maintain ventilation of the alveoli? Why, sometimes, do people die from severe asthma?
What will be an ideal response?
The ________ is the inner lining of the uterus
A) perimetrium B) myometrium C) germinal epithelium D) uterine lumen E) endometrium
A crushed peripheral nerve can be repaired if which of the following is(are) healthy?
A) cell body and dendrite B) neurilemma alone C) dendrites and neurilemma D) cell body and neurilemma