A newly married couple is seeking genetic counseling because they are both carriers of the sickle cell trait. How can the nurse best explain the children's risk of inheriting this disease?
a. Every fourth child will have the disease; two others will be carriers.
b. All of their children will be carriers, just as they are.
c. Each child has a one in four chance of having the disease and a two in four chance of being a carrier.
d. The risk levels of their children cannot be determined by this information.
ANS: C
The sickle cell gene is inherited from both parents; therefore each offspring has a one in four chance of inheriting the disease.
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