The nurse is caring for a patient receiving tolvaptan and digoxin. What drug–drug interaction will the nurse assess for when reviewing this patient's laboratory results?
A) Elevated serum sodium levels
B) Reduced digoxin levels
C) Elevated serum potassium levels
D) Tolvaptan toxicity
C
Feedback:
Tolvaptan should be used with care with digoxin, which could cause hyperkalemia, so the nurse must carefully monitor serum potassium levels. The combination of drugs would not cause reduced digoxin levels or tolvaptan toxicity. The indication for administering tolvaptan would be to treat hyponatremia, so an elevation in serum sodium levels to normal range would be an indication the drug was working but would not be a result of a drug-drug interaction.
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