A client has been prescribed denosumab (Prolia). What medication education should the nurse provide?

Question

1. "I will give your medication in the form of an injection."
2. "You may feel more fatigued than usual when taking this drug."
3. "Be certain to keep your appointments for follow-up."
4. "Do not take any kind of calcium supplement or vitamin D supplement while taking this drug."
5. "We must monitor your cholesterol while you are taking this drug."

Answer 1

1,2,3,5
Rationale 1: Denosumab is given subcutaneously.
Rationale 2: An adverse reaction of this drug is fatigue.
Rationale 3: This drug can cause severe hypocalcemia, so it is important to monitor lab values.
Rationale 4: Calcium and vitamin D supplementation may be necessary to keep serum calcium at normal level.
Rationale 5: This drug may result in hypercholesterolemia.
Global Rationale: Denosumab is given subcutaneously. An adverse reaction of this drug is fatigue. This drug can cause severe hypocalcemia, so it is important to monitor lab values. This drug may result in hypercholesterolemia. Calcium and vitamin D supplementation may be necessary to keep serum calcium at normal level.