Which of the following is necessary for platelet adhesion to collagen?
a. Calcium
b. Fibrinogen
c. VWF
d. Factor XIII
ANS: C
VWF is necessary for normal platelet adhesion to exposed subendothelial collagen. Calcium is a cofactor required for binding of vitamin K-dependent proteins to phospholipids. Fibrinogen is necessary for normal platelet aggregation, whereas factor XIII, in its active form, cross-links the fibrin polymer and thus stabilizes the clot.
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Fill in the blank(s) with correct word
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Fill in the blank(s) with the appropriate word(s).
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