Protein binding is an important aspect of pharmacokinetics. Protein binding ultimately has which of the following effects on drug action?
A) Increases the drug's speed of action
B) Decreases the drug's speed of action
C) Increases the rate of excretion
D) Averts adverse effects
B
Feedback:
Protein binding allows part of a drug to be stored and released as needed. Drugs that are highly bound to plasma proteins or stored extensively in other tissues have a long duration of action. Protein binding does not increase the speed of action, increase the excretion rate, or avert adverse effects. Protein binding decreases the speed of action by storing the drug to be released when needed.
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