Nurses should be aware of the strengths and limitations of various biochemical assessments during pregnancy, including that
a. Chorionic villus sampling (CVS) is becoming more popular because it provides
early diagnosis.
b. Screening for maternal serum alpha-fetoprotein (MSAFP) levels is recommended
between 10 and 12 weeks of gestation in order to give parents time to consider
options.
c. Percutaneous umbilical blood sampling (PUBS) is one of the multiple marker
screen tests for Down syndrome.
d. MSAFP is a screening tool only; it identifies candidates for more definitive
procedures.
D
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A CVS does provide a rapid result, but it is declining in popularity because of
advances in noninvasive screening techniques.
B MSAFP screening is recommended for all pregnant women.
C Screening is recommended between 15 and 20 weeks of gestation. Abnormal
findings give parents time to have additional tests done.
D This is correct, MSAFP is a screening tool, not a diagnostic tool. Further
diagnostic testing is indicated after an abnormal MSAFP.
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