Determine and explain whether a desmosome or a tight junction is the more suitable cell junction for withstanding mechanical stress
What will be an ideal response?
Tight junctions link cells together and make the space between adjacent cells impermeable to the passage of macromolecules. Tight junctions are composed of integral proteins in the plasma membranes of adjacent cells that interweave and lock together, forming a seal around the apical perimeter of the cell. By contrast, desmosomes are composed of integral proteins that connect two cells together by linking to intermediate proteins of the cytoskeleton, which reinforces them. Desmosomes increase the strength of the tissue by holding the cells together so that mechanical stress is more evenly distributed. By the nature of their construction, desmosomes are the more suitable cell junction for withstanding mechanical stress.
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