Shane is a 20-year-old man whose mother was diagnosed with schizophrenia at the age of 25. He is concerned that he may also develop the disorder. Which of the following statements regarding schizophrenia and genetics is most accurate?

A) Schizophrenia has not been shown to be genetic.
B) Schizophrenia can only be passed from a father to his children.
C) Schizophrenia has shown a strong genetic contribution.
D) Schizophrenia can only be passed from a mother to her children.


Ans: C
Feedback:
Many studies strongly suggest a genetic contribution. Relatives of people with schizophrenia have a higher incidence of the disorder than is found in the general population. First-degree relatives (ie, parents, siblings, children) of clients with schizophrenia are at greater risk for the illness than are second-degree relatives (eg, grandparents, grandchildren, aunts, uncles, half-siblings). Schizophrenia is 13% more likely to develop in children with one parent who has schizophrenia than in those with unaffected parents; when both parents have schizophrenia, a child has a 46% risk for the illness (NIMH, 2006).

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