The ELISA test has been used as the most common, rapid screening test for HIV infection. Its sensitivity is very high but its specificity is rather low (for an important identification test). Which statement describes this accurately?
A. A false positive test result may develop due to the test antigens capturing normal antibodies.
B. The patient's specimen has to be handled in a certain way to maintain the integrity of the viral DNA.
C. The test can identify the patient's antibody to HIV only when it is large quantities.
D. Only certain kinds of instruments can be used to pick up the small amounts of fluorescence given off in the ELISA.
Answer: A
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A. NGS involves inserting the genomic fragments into vectors, which is an efficient process compared to using the oligonucleotide adapters employed in the Sanger method B. NGS involves the construction of a genomic library, giving extra depth of coverage compared to the Sanger method C. NGS sequences the same fragment no more than 10 times, avoiding wasteful processes compared to the Sanger method D. NGS avoids the need to insert fragments into cloning vectors, using oligonucleotide adapters that bind to a solid surface instead
Which of the following statements regarding fins on fishes is true?
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What would happen if the body did not produce insulin?
A. Cells of the body would neither take in glucose from the bloodstream nor release it into the blood stream. B. Cells of the body would keep on taking glucose from the bloodstream and storing it. C. Cells of the body would not release glucose into the blood stream when glucose levels were low in the blood stream. D. Cells of the body would not be able to take in glucose, even when glucose levels were high in the blood stream.
An elderly patient presents with blistering of the skin. You suspect an autoimmune disorder. If your suspicions are correct, the patient's serum should contain antibodies reactive to
A) talin. B) vinculin. C) ?-actinin. D) BPAG. E) actin.