A nurse is providing discharge instructions to a patient who is taking atenolol (Tenormin) to treat hypertension. What would the nurse teach the patient regarding a possible drug–drug interaction?
A) Antibiotics
B) Oral contraceptives
C) Nonsteroidal anti-inflammatory drugs (NSAIDs)
D) Antifungal agents
C
Feedback:
A decreased hypertensive effect can occur if a beta-selective adrenergic blocking agent is used in combination with NSAIDs. If this combination is used, the patient should be monitored closely and dosage adjustments made. Antibiotics, oral contraceptives, and antifungal agents are not known to have a drug–drug interaction.
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