In the Ames test, mutagenicity is normally tested on a strain of bacterium (Salmonella typhimurium) that cannot synthesize the amino acid histidine. Therefore, these bacteria require histidine in the growth plate to survive. A researcher performs the Ames test to evaluate the mutagenicity of a newly synthesized compound and notices that Salmonella typhimurium is living on a histidine-free growth plate. What can be concluded from these results?

A. The bacteria produce histidine.
B. The newly synthesized compound induces a mutation in the bacteria and the bacteria no longer produce histidine.
C. The newly synthesized compound induces a mutation in the bacteria and the bacteria produce histidine.
D. The bacteria no longer produce histidine.
E. The newly synthesized compound induces a mutation in the bacteria.


Answer: C

Biology & Microbiology

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