Which values must be known in order to determine a drug's therapeutic range? Note: Credit will be given only if all correct choices and no incorrect choices are selected. Standard Text: Select all that apply
1. Toxic concentration
2. Onset of action
3. Peak plasma level
4. Absorption rate
5. Minimal effective concentration
1,5
Rationale 1: Toxic concentration is an essential determinant of therapeutic range.
Rationale 2: Onset of action is not related to therapeutic range.
Rationale 3: Peak plasma level is not related to therapeutic range.
Rationale 4: Absorption rate is not related to therapeutic range.
Rationale 5: Minimal effective concentration is an essential determinant of therapeutic range.
Global Rationale: Therapeutic range is the area between toxic concentration and minimum effective concentration. Onset of action, peak plasma level, and absorption rate are not related to therapeutic range.
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A patient must void some before the clean catch is collected
True False