In chickens, there is a mutant gene called "frizzle" that results in weak, stringy, and easily broken feathers. When a frightfully frizzled fowl is bred to a normal chicken, the offspring are all mildly frizzled
If one breeds two mildly frizzled chickens to each other, the offspring have the phenotypic ratio of 1 normal: 2 mildly frizzled: 1 frightfully frizzled. What is the mode of inheritance of "frizzle"?
There are three phenotypes observed in the F1 offspring in the ratio of 1:2:1, and one phenotype is intermediate between the other two. This is the signature of incomplete dominant inheritance. The normal chicken represents the homozygous wild-type genotype, the mildly frizzled chickens are heterozygotes, and the frightfully frizzled chicken has homozygous mutant phenotypes.
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