What is the primary advantage of using monoclonal antibodies (MABs) rather than polyclonal antibodies?
1. Oral administration
2. Single dosing
3. Broad-spectrum use
4. Fewer side effects
Correct Answer: 4
Rationale 1: Monoclonal antibodies are administered intravenously.
Rationale 2: Monoclonal antibodies require multiple dosing.
Rationale 3: Monoclonal antibodies have a narrow spectrum of use.
Rationale 4: Fewer adverse effects are the primary advantage of MABs.
Global Rationale: Because a single B cell produces a single antibody, it is called a monoclonal antibody (MAB). A MAB is very specific, targeting a single type of target cell or receptor. This allows greater effects on the target cell or receptor at lower doses and with fewer adverse effects than using polyclonal antibodies. These drugs are administered intravenously, require multiple dosing, and have a narrow spectrum of use.
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The final section of a performance appraisal is a rating scale. This scale is very detailed and relates to competency standards specific to surgical clients
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