Conivaptan (Vaprisol) is prescribed for a client with severe SIADH. The nurse preparing this medication recognizes that the desired outcome of this therapy is:
1. a decreased urine output.
2. an increased urine output.
3. an increased blood pressure.
4. an increased heart rate.
Correct Answer: 2
Rationale 1: Conivaptan (Vaprisol) does not cause a decrease in urine output.
Rationale 2: Conivaptan blocks receptors in the kidneys that normally bind to ADH. With less ADH, there is less antidiuresis. Less antidiuresis means more urine is produced and eliminated.
Rationale 3: Conivaptan (Vaprisol) does not increase blood pressure.
Rationale 4: Conivaptan (Vaprisol) does not increase the heart rate.
Global Rationale: Conivaptan blocks receptors in the kidneys that normally bind to ADH. With less ADH, there is less antidiuresis. Less antidiuresis means more urine is produced and eliminated. It is not given to increase blood pressure or heart rate.
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