A client is admitted to the emergency department for an infection. The nurse recognizes that host factors that play a role in the selection of anti-infective therapy include:
Standard Text: Select all that apply.
1. status of immune system.
2. location of the infection.
3. history of allergic reactions.
4. previous infections.
5. results of culture and sensitivity (C&S).
Correct Answer: 1,2,3
Rationale 1: Clients with a weakened immune system may require more aggressive and prolonged anti-infective therapy.
Rationale 2: The location of the infection must be considered in order to choose the most effective anti-infective.
Rationale 3: A history of allergic reaction to an anti-infective prevents the use of that particular class.
Rationale 4: Previous infections are not taken into consideration when prescribing an anti-infective for a current infection.
Rationale 5: The results of the C&S are important to the selection of the anti-infective but are not a host factor.
Global Rationale: Patient factors such as host defenses, local tissue conditions, history of allergic reactions, age, pregnancy status, and genetics influence the choice of anti-infective.
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