The nurse is caring for an obese client who has received thiopental (Pentothal), a lipid-soluble drug, during surgery. Of which fact about the drug should the nurse be aware?
1. It will need to be given at higher than normal doses.
2. It will be stored in adipose tissue.
3. It may have difficulty being distributed to body tissues.
4. It is often ineffective.
Correct Answer: 2
Rationale 1: Higher doses of the drug are not necessary.
Rationale 2: Thiopental is a lipid-soluble drug that has a higher affinity for bone marrow, teeth, the eye, and adipose tissue.
Rationale 3: Lipid-soluble drugs are more completely distributed to body tissues.
Rationale 4: The efficacy of the drug is not affected by the lipid solubility.
Global Rationale: Thiopental is a lipid-soluble drug that has a higher affinity for bone marrow, teeth, the eye, and adipose tissue. Higher doses of the drug are not necessary. Lipid-soluble drugs are more completely distributed to body tissues. The efficacy of the drug is not affected by the lipid solubility.
You might also like to view...
A nurse assesses a client with a brain tumor. The client opens his eyes when the nurse calls his name, mumbles in response to questions, and follows simple commands. How should the nurse document this client's assessment using the Glasgow Coma Scale shown
a. 8 b. 10 c. 12 d. 14
The nurse is preparing a patient's body following death. The patient's dentures were not in his mouth prior to death. The nurse should:
1. insert them gently into the mouth. 2. give them to the family. 3. throw them away. 4. send them to waste management to be disposed of properly.
A nurse is using motivational therapy with a female client with alcoholism. The client, who is unwilling to consider changing her drinking behavior, emphatically states, "I am not an alcoholic; you can't make me stop drinking"
Which response by the nurse would be most appropriate? A) "You have to stop drinking and driving; you could kill someone." B) "You're right; you're not an alcoholic." C) "You should consider what you are doing to your marital relationship." D) "You're the only one who can make yourself stop drinking."
You are preparing to give an unfamiliar drug to a patient. What information must you review before administering the drug? (Select all that apply.)
A. Drug's purpose B. Drug's side effects C. Patient's drug allergies D. Last time the drug was administered to the patient E. Drug's chemical name