A patient who frequently takes diphenhydramine (Benadryl) to prevent motion sickness is scheduled for skin testing to diagnose possible allergies. For what number of days should the pa-tient refrain from taking diphenhydramine before skin testing?
a. 1
b. 2
c. 4
d. 7
ANS: C
Allergy skin testing may be falsely negative in patients taking dimenhydrinate, diphenhydramine, and meclizine at the time of testing. Discontinue diphenhydramine 4 days before testing.
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