The physician has ordered combination therapy for the client with peptic ulcer disease (PUD). The nurse plans to do medication education. What will the best plan by the nurse include?

1. Combination therapy has the best outcomes when antibiotics are used with antacids.
2. Combination therapy has the best outcomes when antibiotics are used with proton-pump inhibitors.
3. The use of sucralfate (Carafate) along with antibiotics is the best combination therapy for peptic ulcer disease (PUD).
4. Various antibiotics are used to eradicate the bacteria that are responsible for the development of peptic ulcer disease (PUD).


Correct Answer: 2
Rationale 1: Combination therapy has the best outcomes when antibiotics are used with proton-pump inhibitors, not with antacids.
Rationale 2: Combination therapy has the best outcomes when antibiotics are used with proton-pump inhibitors.
Rationale 3: Combination therapy has the best outcomes when antibiotics are used with proton-pump inhibitors, not with sucralfate (Carafate).
Rationale 4: Combination therapy has the best outcomes when antibiotics are combined with proton-pump inhibitors, rather than when used alone.

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