A child who weighs 10 kg will begin taking oral trimethoprim-sulfamethoxazole (TMP-SMX). The liquid preparation contains 40 mg of TMP and 200 mg of SMX per 5 mL
The nurse determines that the child's dose should be 8 mg of TMP and 40 mg of SMX/kg/day divided into two doses. Which order for this child is correct?
a. 5 mL PO BID
b. 5 mL PO daily
c. 10 mL PO BID
d. 10 mL PO daily
ANS: A
This child should receive (10 kg ? 8 mg) 80 mg of TMP and (10 kg ? 40 mg) 400 mL of SMX per day. When divided into two doses, the correct dose is 40 mg TMP and 200 mg SMX, or 5 mL per dose.
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