A 30-year-old presents with hypertension, headache, tachycardia, impaired glucose tolerance, and weight loss. Which of the following diagnoses is supported by this symptomology?
a. Addison disease
b. Conn disease
c. Cushing disease
d. Pheochromocytoma
ANS: D
Symptoms of pheochromocytoma include hypertension, palpitations, tachycardia, glucose intol-erance, excessive sweating, and constipation. Manifestations of Addison disease include weak-ness, fatigability, hypoglycemia and related metabolic problems, lowered response to stressors, hyperpigmentation, vitiligo, and manifestations of hypovolemia and hyperkalemia. Hypertension and hypokalemia are the hallmarks of Conn disease. Weight gain is the most common feature in Cushing disease and results from the accumulation of adipose tissue in the trunk, facial, and cer-vical areas. These characteristic patterns of fat deposition have been described as "truncal obesi-ty," "moon face," and "buffalo hump."
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