Which immunodeficiency disease is caused by a defect in the phagocyte NADPH oxidase system, and what is the cellular effect of this defect?
What will be an ideal response?
Chronic granulomatous disease is caused by defects in phagocyte NADPH oxidase. Phagocytes with this defect cannot produce superoxide radicals and are less effective at intracellular killing of ingested bacteria. Macrophages infected with bacteria that they cannot kill form the granulomas characteristic of this condition.
You might also like to view...
Arteritis is an inflammation of an artery
Indicate whether the statement is true or false
Which of the following is NOT a defining characteristic of transgender individuals?
A. experiencing emotional and sexual attraction to members of the same sex B. identifying strongly with the other sex C. experiencing a sense of inappropriateness about one’s sex D. having a sense of identity as male or female that conflicts with one’s biological sex
Describe how an internal customer is created.
What will be an ideal response?
A test administrator's opinions, understanding, and evaluation of the test outcome can influence test accuracy, which is defined as?
A. objectivity B. validity C. reliability D. affective