Many antineoplastic agents have characteristics of more than one class. Paclitaxel (Taxol) can be classified as a(n):
Standard Text: Select all that apply.
1. natural product.
2. taxane.
3. mitotic inhibitor.
4. cell cycle inhibitor.
5. alkylating agent.
Correct Answer: 1,2,3,4
Rationale 1: Paclitaxel (Taxol) can be classified as a natural product (it was derived from a plant).
Rationale 2: Paclitaxel (Taxol) can be classified as a taxane (its chemical structure).
Rationale 3: Paclitaxel (Taxol) can be classified as a mitotic inhibitor (its mechanism of action).
Rationale 4: Paclitaxel (Taxol) can be classified as a cell cycle inhibitor.
Rationale 5: Paclitaxel (Taxol) is not classified as an alkylating agent.
Global Rationale: Paclitaxel (Taxol) can be classified as a natural product (it was derived from a plant), a taxane (its chemical structure), a mitotic inhibitor (its mechanism of action), or a cell cycle inhibitor. It is not classified as an alkylating agent.
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