Match each receptor listed in questions 8-14 with the lettered ligand (A-E) that binds to the receptor. (Answers may be used more than once.)

A. B7-1, B7-2
B. Class II MHC
C. LFA-3
D. VCAM-1
E. Sialylated Lewis

VLA-4


ANS: D.  VLA-4, an integrin expressed on T cells, binds to VCAM-1, an Ig superfamily member expressed on activated endothelium. VLA-4-VCAM-1 interactions promote T cell recruitment into inflammatory sites.

Health & Biomechanics

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Fill in the blank(s) with correct word

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