A client with primary hypertension is prescribed terazosin (Hytrin) to treat this condition
When teaching the client about how this drug works to decrease blood pressure, which mechanism of action provides the rationale for the use of the medication?
A) Prevents conversion of angiotensin I to angiotensin II.
B) Prevents beta-receptor stimulation in the heart.
C) Inhibits the flow of calcium ions across the cell membrane of vascular tissue and cardiac cells.
D) Blocks alpha-receptors in the vascular smooth muscle.
Answer: D
Terazosin (Hytrin), an alpha-adrenergic blocker, acts by blocking alpha-receptors in the vascular smooth muscle. ACE inhibitor medications prevent conversion of angiotensin I to angiotensin II. Beta-adrenergic blockers prevent beta-receptor stimulation in the heart. Calcium channel blockers inhibit the flow of calcium ions across the cell membrane of vascular tissue and cardiac cells.
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