For each description of a molecule involved in lymphocyte migration in questions 8-12, choose the lettered description (A-I) that most closely matches it

A. Peripheral lymph node addressin
B. Intercellular adhesion molecule-1 (ICAM-1)
C. Very late activation antigen-4 (VLA-4)
D. E-selectin
E. P-selectin ligand
F. CCR7
G. CXCR5
H. MadCAM-1
I. Vascular cell adhesion molecule-1 (VCAM-1)

This molecule binds SLC and ELC and is involved in naive T cell migration into interfollicular zones of lymph nodes.


ANS: F.  SLC and ELC are the chemokines that bind to CCR7 on naive T lymphocytes and dendritic cells, and direct their migration into lymph nodes.

Health & Biomechanics

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The circulatory route through a lymphoid tissue for both immature B cells and mature B cells that do not encounter specific antigen is:

a. bloodstream ?HEV of lymphoid cortex ? primary lymphoid follicle ? efferent lymphatic vessel b. afferent lymphatic vessel ? primary lymphoid follicle ?HEV of lymphoid cortex ?efferent lymphatic vessel c. afferent lymphatic vessel ?medullary cords ? primary lymphoid follicle ?efferent lymphatic vessel d. primary lymphoid follicle ?HEV of lymphoid cortex ?afferent lymphatic vessel ?efferent lymphatic vessel e. bloodstream ?afferent lymphatic vessel ? HEV of lymphoid cortex ?efferent lymphatic vessel.

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An otoscope is an instrument for visually examining the ____________________.

Fill in the blank(s) with the appropriate word(s).

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A condition characterized by reduced muscle tone is called:

A. aphasia. B. catatonia. C. dyslexia. D. dyskinesia. E. dementia.

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