Which elevated serum marker for systemic inflammation is now considered a major risk factor for atherosclerosis and vascular disease?
A) Leukocytosis
B) Homocysteine
C) Serum lipoprotein
D) C-reactive protein
Ans: D
Feedback:
CRP is an acute-phase reactant synthesized in the liver that is a marker for systemic inflammation. A number of population-based studies have demonstrated that baseline CRP levels can predict future cardiovascular events among apparently healthy individuals. High-sensitivity CRP (hs-CRP) may be a better predictor of cardiovascular risk than lipid measurement alone. Homocysteine and serum lipoprotein are also serum markers, but they do not identify inflammation. Leukocytosis is an indicator of infection rather than inflammation alone.
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