The highest degree of diversity resulting from somatic recombination is concentrated ____________ of the VH and VL domains, whereas the point mutations caused by somatic hypermutation are found ____________

a. in CDR3; throughout the V region
b. in CDR3; in CDR1 and CDR2 of VH and VL domains
c. in CDR1 and CDR2; in CDR3
d. in CDR1 and CDR2; throughout the V region
e. in all three CDRs; in C regions.


A

Health & Biomechanics

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