Why do some patients develop nausea and vomiting after taking aspirin?
A. Salicylates stimulate the mucopolysaccharides in the stomach causing hydrochloric acid erosion that leads to nausea and vomiting.
B. Salicylates stimulate the microsomal metabolizing system in the liver, resulting in an increase in the amount of acid produced in the GI tract.
C. Salicylates stimulate the medullary center known as the chemoreceptor trigger zone that directly excites the vomiting center so that emesis may occur.
D. None of the above are correct.
Answer: C
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