The pathophysiologic consequences of respiratory syncytial virus include
a. replacement of the epithelium with nonciliated tissue, leading to submucosal edema and eventual necrosis.
b. necrosis of the alveoli, resulting in collapse.
c. inflammation of the diaphragm, resulting in alveolar hypoventilation.
d. bronchoconstriction, resulting in severe airflow obstruction.
A
Respiratory syncytial virus involves inflammation of respiratory epithelium, leading to necrosis. The epithelium is replaced with nonciliated tissue. Submucosal edema forms with lymphocytic infiltrates and other alveolar debris. Obstruction occurs from mucus secretions and debris not being cleared because of the lack of ciliated epithelium.
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