Tacrolimus (FK-506) is a drug that inhibits an enzyme called calcineurin. Calcineurin is a protein phosphatase. This is an enzyme that dephosphorylates (removes phosphate groups) from proteins. When added to cells, tacrolimus can inhibit the dephosphorylation of a protein called NFAT, but it cannot prevent the dephosphorylation of a protein called CDK1 . What is the most likely explanation for
this finding?
A. Calcineurin requires an additional cofactor to dephosphorylate NFAT
B. NFAT is a substrate of calcineurin, but CDK1 is not
C. Tacrolimus is a competitive inhibitor of calcineurin for NFAT and CDK11
D. Tacrolimus changes the optimum pH for calcineurin
B
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A) epithelial tissue. B) adipose tissue. C) endocrine glands. D) connective tissue. E) muscle tissue.
During what process are hypochlorite and hydrogen peroxide produced to destroy bacteria and inhibit viral replication?
A. inflammation B. phagocytosis C. complement production D. lysozyme production E. interferon production
What is the advantage of a fungal body being composed of numerous thin hyphae instead of one or two very thick hyphae?
A. A greater surface area is available for absorption of nutrients. B. Less energy is required to produce the hyphae. C. Better support is provided by numerous hyphae. D. More exposure to the sun allows for increased photosynthesis. E. All the answer options are correct.
Saprobes do not need a carbon source for growth and metabolism.
Answer the following statement true (T) or false (F)