It has been found that a particular "+ –" combination of frameshift mutations in gene X gives a wild-type phenotype, whereas a "– +" combination gives a mutant phenotype, even though the sites of insertion/deletion are the same

How might these results be explained?


A frameshift in the "+ –" direction may have introduced a nonsense triplet, which was not introduced, by chance, by the opposite "– +" combination.

Biology & Microbiology

You might also like to view...

DNA sequencing can reveal

A) mutations that do not alter phenotype. B) mutations that do not alter genotype. C) which tissues express a gene. D) how many genes a person has.

Biology & Microbiology

Both plants and animals possess mitochondria, which are used for cellular respiration to make ATP

Indicate whether the statement is true or false.

Biology & Microbiology

The figure shown above is of what kind of

tissue? a. blood b. adipose c. bone d. cartilage e. dense connective

Biology & Microbiology

Which type of test is particularly useful in analyzing tumors in tissues surrounded by bone?

A. PSA B. CAT scan C. Pap test D. MRI E. X-ray

Biology & Microbiology