If an HIV-infected patient has an adverse reaction to the treatment of choice for Pneumocystis jiroveci pneumonia, what treatment should be instituted?
a. Amphotericin B
b. Pentamidine
c. Trimethoprim-sulfamethoxazole
d. Vancomycin
ANS: B
Up to 50% of HIV-infected patients will develop fever or a rash while taking TMP-SMX. Pen-tamidine is an acceptable alternative.
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